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Diabetes and pancreatic cancer: What is the connection?
What is the purpose of the study?
The PANDOME study aims to detect pancreatic cancer in its earliest stages by using magnetic resonance imaging (MRI). Individuals over 50 years of age with new-onset diabetes (NOD) or deteriorating diabetes (DD) may be eligible for screening. NOD is diabetes that has been diagnosed within the past 12 months. DD is long-standing diabetes that seems difficult to control (HbA1c increase of >2%). Both NOD and DD are associated with an increased risk of pancreatic cancer.
Are you eligible to participate?
- Are you at least 50 years of age?
- Have you been diagnosed with diabetes within the past 12 months or has your long-standing diabetes become difficult to control recently?
- Are you able to undergo an MRI?
What is the study plan?
If enrolled in the trial, you will undergo a magnetic resonance imaging (MRI) scan of the pancreas. Research staff will also evaluate your overall health every 6 months and obtain a blood sample for research purposes. Before participation, risks and benefits will be explained in detail during a process called informed consent.
Who will pay for the MRI tests and other study procedures?
Nuvance Health will cover the costs of MRI examinations AND other study related costs through philanthropic donations.
Is this study being performed at other centers?
Yale University is now included as a study center, and will be recruiting participants soon.
Who is leading the study?
The principal investigators of the study include Richard Frank, MD, director of cancer research at Nuvance Health and James Farrell, MD, at Yale University.
Are you eligible to participate?
If you would like to see if you are eligible to participate in the PANDOME cancer screening study, please complete the form.
For questions or additional information contact Tammy Lo, APRN at (203) 855-3551 or [email protected].
Cindy's journey: From uncontrolled diabetes to early pancreatic cancer detection and hope
The 82-year-old from Fairfield County, Connecticut, felt both overwhelmed by her pancreatic cancer diagnosis and grateful to have participated in a study that led to its early detection—a rare occurrence for this type of cancer.
Media coverage of our study
Dr. Frank spoke with WICC600’s Melissa in the Morning about pancreatic cancer during National Pancreatic Cancer Awareness Month. His interview starts at 9:12.
CT Insider spoke with Dr. Frank and a pancreatic cancer screening study participant who had complex surgery to remove a pre-cancerous lesion on his pancreas.
Dr. Frank spoke with Radio Health Journal about pancreatic cancer symptoms, research and progress towards finding the disease at an earlier stage.
Dr. Frank spoke with U.S. News & World Report about the first signs of pancreatic cancer.