Gynecologic Cancer Research

Learn more about gynecologic cancer research at the Rudy L. Ruggles Biomedical Research Institute.

The Rudy L. Ruggles Research Institute conducts research on gynecologic cancers to improve opportunities for prevention, early diagnosis and treatment. The gynecologic cancer research team at Nuvance Health® focuses on precision medicine therapy, using genes and proteins within individual tumors to deliver targeted treatment.

Identifying Biomarkers

Researchers are identifying cancer-specific biomarkers within the tumor and circulating in the bloodstream that are unique to each patient. Monitoring these biomarkers helps oncologists (cancer specialists) carry out disease surveillance in real time and monitor the effects of treatment.

Participating in Gynecologic Cancer Research

The Rudy L. Ruggles Biomedical Research Institute works closely with Nuvance Health oncologists to find research participants. Learn more about the Nuvance Health Cancer Institute.  

The gynecologic oncology research team focuses on projects including:

The Gynecologic Cancer Research Team


John Martignetti, MD, PhD

Dr. Martignetti directs the team, working closely with cancer surgeons and doctors across Nuvance Health. He also serves as a professor at the Icahn School of Medicine at Mount Sinai.

Sabina Swierczek - Research Assistant

Sabina Swierczek, PhD

Dr. Swierczek is a Lead Research Associate at the Rudy L. Ruggles Biomedical Research Institute at Nuvance Health and Research Assistant Professor at University of Vermont’s College of Medicine. She has 25 years of experience in immunology, biochemistry, molecular biology, hematological malignancies and cancers. 

Dr. Swierczek also leads research on the generation and characterization of preclinical models. This research aims to reflect the underlying genetics and biology of gynecological cancers, which will define the tumor’s biology and help develop novel therapeutic approaches. She is co-author on more than 45 peer-reviewed scientific papers.


Fuat Kaplan

Fuat Kaplan, MS

Fuat Kaplan is a J1 Research Scholar working on his PhD thesis at the Rudy L. Ruggles biomedical research institute at Nuvance Health. His thesis focuses on a comparison of cancer driver mutations of cfDNA and tumor tissue samples. He has expertise in cell culture, PCR, qRT-PCR and western blot.
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